This is a somewhat opinionated minimal set of customisations for Emacs when running on macOS that give me a good baseline quality of experience.
Keys
My expectation from a lifetime of keyboards is that the modifier keys are Ctrl, Alt and
Meta, in that order, to the left of the spacebar, and Meta, Alt and Ctrl to the right of
the spacebar. This means that on a macOS keyboard I need to map Cmd to Meta and Option to
Alt.
The only problem is that macOS already uses Option for symbol entry so I want to leave Left
Option unchanged and only bind Right Option to Alt.
I've also gradually discovered that Super is often useful in Emacs so I have chosen to bind
Right Cmd to Super.
(setopt mac-command-modifier 'meta)
(setopt mac-right-command-modifier 'super)
(setopt mac-option-modifier nil)
(setopt mac-right-option-modifier 'alt)
I have grown used to the macOS keysfor hiding an app with Cmd-h and for window cycling with
Cmd-`. Unfortunately Emacs has existing bindings for these keys that prevent this, so I need
to set them back to the desired behaviour.
(keymap-set global-map "M-h" 'ns-do-hide-emacs)
(keymap-set global-map "M-`" 'other-frame)Appearance
Visual appearance is probably the most subjective thing about any configuration. Here I am
focused on the basics — a dark theme, provided by tango-dark, with uncluttered UI and
maximised editor real-estate.
In my Emacs lifetime, the tool bar is something I have never used and don't give screen space to. The same goes for the scroll bar. The fringe, on the other hand, is genuinely useful and I like to have the left fringe enabled.
(setopt custom-enabled-themes '(tango-dark))
(setopt default-frame-alist '((width . 120) (height . 98) (top . 25)))
(setopt scroll-bar-mode nil)
(setopt tool-bar-mode nil)
(setopt fringe-mode '(nil . 0))
(setopt inhibit-startup-screen t)With optional clutter removed, my iMac can show a frame that is 120 columns by 98 rows, taking up almost exactly a vertical third of the screen. This lets me have three equally sized frames visible.

Modes that improve UX
There are some global minor modes that switch on valuable functionality throughout Emacs.
(column-number-mode t)
(which-key-mode t)
(pixel-scroll-precision-mode t)
(setopt mode-line-collapse-minor-modes t)column-number-modeextends adds the cursor column to the modeline after the cursor line number.which-key-modedisplays key bindings that can follow the current partial command. For example, typingC-x 8will reveal the keys for inserting special characters.pixel-scroll-precision-modeenables smooth scrolling of buffers that contain inline images, instead of treating the whole image as a single scroll line.

C-x 8 key bindings.
Minor modes usually get displayed on the modeline so it's great to be able to hide them and save
modeline real-estate for more valuable information. mode-line-collapse-minor-modes is a brand
new option that does exactly this.